SL Benfica - Académica de Coimbra (17/02/13)

Hélder Cabral (Académica) 90+3'
1-0 Lima (pen.) 90+4'

Rio Ave FC - Sporting Braga (18/02/13)

1-0 Ahmed Mahgoub 3'
1-1 Alan (pen.) 45+3'
Ahmed Mahgoub 88'

Gil Vicente - Sporting CP (16/02/13)

0-1 Bruma 1'
0-2 Tiago Abiola Delfim Almeida Ilori 6'
1-2 Hugo Vieira 20'
2-2 Hugo Vieira 53'
2-3 Diego Capel 63'

SC Olhanense - Vitória Setúbal (17/02/13)

0-1 Paulo Tavares 81'

Paços de Ferreira - CD Nacional (17/02/13)

1-0 Cícero 22'
1-1 Bruno Moreira 77'

CS Marítimo - GD Estoril (17/02/13)

1-0 Leocísio Júlio Sami 8'
2-0 David Simão (pen.) 22'
Hyun-Jun Suk (Marítimo) 54'
2-1 Evandro Goebel 58'
Yohan Tavares (Estoril) 75'

Vitória Guimarães - Moreirense FC (17/02/13)

1-0 Leonel Olimpio (pen.) 8'